TriMix Injection — Online ED Evaluation
TriMix is a compounded prescription injection (commonly including alprostadil, papaverine, and phentolamine) that may be used for erectile dysfunction (ED). A licensed clinician will determine if TriMix is appropriate for you after evaluation and training.
Real medicine. Real results.

What to know about TriMix
TriMix is an individualized, compounded sterile injection prepared by licensed compounding pharmacies. Formulations and strengths vary based on clinical judgment. Patients receive instruction on proper self-injection technique, dosing, and needle disposal.
Rx only Compounded medication Clinician-directed
- Used when clinically appropriate for adult patients after evaluation and training
- Dose is individualized; follow your clinician’s titration plan precisely
- Rotate injection sites; do not exceed prescribed frequency
- Do not combine with other ED therapies unless your clinician advises
The 3 in 1 Power Behind Trimix
Trimix is a compounded injection that combines three medications: papaverine, phentolamine, and prostaglandin E1. This powerful combo relaxes smooth muscle and widens blood vessels in the penis—helping you achieve a firm, long-lasting erection, often quickly and without relying on arousal, when a clinician determines it’s appropriate.
Important Safety Info
- Seek urgent medical care for an erection lasting more than 4 hours (priapism).
- Use only as directed by your clinician; do not exceed prescribed dose or frequency.
- Tell your clinician about penile curvature/Peyronie’s disease, bleeding risks, blood disorders (e.g., sickle cell), or leukemia.
- Do not combine with other ED medications unless specifically instructed by your clinician.
- Compounded medications are prepared by licensed compounding pharmacies and are not FDA-approved.
How it works
1) Secure intake → 2) Clinician review (telehealth if needed) → 3) If appropriate, training & dosing plan are provided. Prescriptions are not guaranteed.
Safety first
Seek urgent care for an erection lasting >4 hours (priapism). Tell your clinician about penile curvature, blood disorders, anticoagulants, or bleeding risks.
Dispensing
TriMix is compounded and dispensed by a state-licensed U.S. compounding pharmacy and shipped where permitted. Supplies (syringes/needles) and disposal guidance are provided.
TriMix FAQs
Is TriMix FDA-approved?
No. TriMix is a compounded medication prepared by licensed compounding pharmacies for individual patients and is not FDA-approved. Formulation and strength may vary.
Will I be trained to self-inject?
Yes. If prescribed, your clinician will review sterile technique, site selection, needle handling, dosing, and what to do in case of prolonged erection or adverse effects.
How often can I use TriMix?
Only as directed. Frequency limits are set by your clinician to reduce risks; do not exceed your prescribed dose or schedule and rotate injection sites.
Can I use TriMix with sildenafil or tadalafil?
Do not combine TriMix with other ED medications unless your clinician specifically advises. Combining therapies may increase risks.
How will I receive my medication?
If prescribed, TriMix is dispensed by a state-licensed U.S. compounding pharmacy and shipped where permitted by law. Availability may vary by state and regulation.
Important: Medications are prescribed only when clinically appropriate after a valid clinician-patient relationship is established. Compounded medications are not FDA-approved. Follow your clinician’s instructions and seek emergency care for an erection lasting more than 4 hours.